Leukemia

Comprehensive Look at Rare Leukemia Finds Relatively Few Genetic Changes Launch Disease

Published in Genetics and Environmental Business Week, August 13th, 2009

The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps, according to new findings from St. Jude Children's Research Hospital. The research appears in the July 27 online edition of the Proceedings of the National Academy of Sciences.

"Our data raise the possibility that the development of AML may require fewer genetic alterations than other cancers and that a very limited number of biological processes may need to be altered in hematopoietic stem cells, multi-potential progenitors or committed myeloid progenitors to convert...

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Source: Genetics and Environmental Business Week (2009-08-13)

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