Glioma

New glioma study results reported from University of Illinois

Published in Genetics and Environmental Business Week, November 12th, 2009

According to a study from the United States, "Malignant gliomas are characterized by invasive and infiltrative behavior that generally involves the destruction of normal brain tissue. Strategies to treat infiltrating gliomas, such as chemotherapy and gene therapy, have remained largely unsuccessful."

"The infiltrative nature of gliomas can be attributed largely to proteases, which include serine, metallo- and cysteine-proteases. Our previous work and that of others strongly suggest a relationship between the expression of uPAR, MMP-9, and MMP-2; this relationship is generally indicative of the infiltrative phenotype of gliomas. In the present study, we have demonstrated...

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Source: Genetics and Environmental Business Week (2009-11-12)

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