Life Sciences

Reports outline life sciences study findings from M. Sadelain and colleagues

Published in Genetics and Environmental Business Week, February 11th, 2010

"The adoptive transfer of tumor-reactive cells is a promising approach for the treatment of melanoma and some other cancers. To remedy the difficulties associated with the isolation and expansion of tumor-reactive T cells in most cancer patients, peripheral blood T cells can be retargeted to any chosen tumor antigen by the genetic transfer of an anti gen-specific receptor," investigators in the United States report.

"The transduced receptors may be human leukocyte antigen-restricted, heterodimeric T-cell antigen receptor (TCRs), or chimeric antigen receptors (CARs), which typically recognize native cell-surface antigens. Considerable progress has been made in recent...

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Source: Genetics and Environmental Business Week (2010-02-11)

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