Bipolar Disorder

New findings from RIKEN describe advances in bipolar disorder

Published in Genetics and Environmental Business Week, February 11th, 2010

According to a study from Wako, Japan, "Recent progress in genotyping technology and the development of public databases has enabled large-scale genome-wide association tests with diseases. We performed a two-stage genome-wide association study (GWAS) of bipolar disorder (BD) in Japanese cohorts."

"First we used Affymetrix 100K GeneChip arrays in the analysis of 107 cases with bipolar I disorder and 107 controls, and selected markers that were nominally significant (P <0.01) in at least one of the three models (1,577 markers in total). In the follow-up stage, we analyzed these markers using an Illumina platform (1,526 markers; 51 markers were not designable for the...

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Source: Genetics and Environmental Business Week (2010-02-11)

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