Acute Leukemia Genetics
Researchers from Fujian Medical University, Department of Hematology publish findings in acute leukemia genetics
Published in Genetics and Environmental Business Week, March 18th, 2010
Data detailed in 'Deficient histone acetylation in acute leukemia and the correction by an isothiocyanate' have been presented. According to a study from Zhangzhou, People's Republic of China, "Since histone hypoacetylation due to excess histone deacetylases (HDACs) has been associated with transcriptional repression in leukemia, we aimed to determine deficient histone acetylation in patients with acute leukemia and the effect of its correction by an isothiocyanate. The acetylation status of histones H3 and H4 in cells from patients with untreated acute leukemia was determined by Western blot."
"Deficient histone acetylation was analyzed in relation to the disease...
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