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CUNY Mt. Sinai School of Medicine

Chlorpyrifos may harm fetal neurodevelopment in mothers with low PON1 levels

Published in Genetics and Environmental Health Week, May 5th, 2004

Chlorpyrifos may harm fetal neurodevelopment in mothers with low PON1 levels.

"Although the use of pesticides in inner-city homes of the United States is of considerable magnitude, little is known about the potentially adverse health effects of such exposure. Recent animal data suggest that exposure to pesticides during pregnancy and early life may impair growth and neurodevelopment in the offspring.

"To investigate the relationship among prenatal pesticide exposure, paraoxonase (PON1) polymorphisms and enzyme activity, and infant growth and neurodevelopment, we are conducting a prospective, multiethnic cohort study of mothers and infants delivered...

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