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Tampere University, Finland

Mannan-binding lectin is a co-factor in the development of atherosclerosis

Published in Genetics and Environmental Health Week, January 5th, 2005

A recent report described the effect of mannan-binding lectin variant alleles on coronary artery reactivity in healthy young men.

According to the report from Finland, "Mannan-binding lectin (MBL) is a serum acute-phase protein and a complement component secreted by the liver. Its deficiency caused by point mutations in the MBL gene has recently been associated with severe atherosclerosis. In [our] study, we investigated the effect of MBL variant alleles on coronary artery reactivity, which is an early marker of coronary dysfunction and predicts the development of atherosclerosis and coronary artery disease."

J. Aittoniemi and colleagues of Tampere...

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