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Alexion Pharmaceuticals, Inc.

Alexion Pharmaceuticals' antibody therapy shown effective in model for allergic asthma

Published in Genetics and Environmental Health Week, June 14th, 2006

Alexion Pharmaceuticals, Inc., (ALXN) announced research findings showing that its anti-C5 monoclonal antibody can be effectively delivered to the lungs to substantially block airway inflammation and hyperresponsiveness in preclinical models of acute severe allergic asthma.

The compound used in the research is a surrogate of eculizumab, Alexion's lead anti-complement antibody. The study shows that anti-C5 monoclonal antibodies, including eculizumab, can be successfully aerosolized for therapeutic use.

The data were presented at the annual meeting of the American Association of Immunologists in Boston by Yi Wang, PhD, Senior Research Fellow at...

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