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Lung Disease Therapy

Data from Ludwig-Maximilians University advance knowledge in lung disease therapy

Published in Genetics and Environmental Health Week, January 17th, 2007

New research, "Anti-inflammatory cytokines in cystic fibrosis lung disease," is the subject of a report. "Lung inflammation plays a pivotal role in the pathogenesis of airway disease in cystic fibrosis (CF). An imbalance between pro-and anti-inflammatory mediators has been observed and a deficiency in the anti-inflammatory response has been proposed, but this concept remains controversial," investigators in Munich, Germany report.

"In the present study, the concentrations of two anti-inflammatory mediators, lipoxin A (LxA4) and Clara cell protein 10 (CC-10), were assessed in bronchoalveolar lavage fluid (BALF) of CF patients with a wide range of endobronchial...

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