Apoptosis

Research from M.A. Maire and co-authors yields new data on apoptosis

Published in Genetics and Environmental Health Week, October 24th, 2007

According to recent research published in the journal Mutation Research - Genetic Toxicology and Environmental Mutagenesis, "'2,4-Dichlorophenoxyacetic acid (2,4-D) is a selective, systemic auxin-type herbicide extensively used throughout the world. The present research was aimed at studying effects of low and non-cytotoxic concentrations of 2,4-D on SHE cells in relation with carcinogenicity."

"Effects were studied on Syrian hamster morphological cell transformation, c-Myc expression - both at the gene and protein level - DNA damage and apoptosis. 2,4-D significantly induced cell transformation at 11.5 mc M and 23 mc M (i.e. 2.5 mu g/mL and 5 mu g/mL). An...

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Source: Genetics and Environmental Health Week (2007-10-24)

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