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Alcoholism

GABRA2 genotype may moderate alcohol-psychotherapy outcomes

Published in Genetics and Environmental Health Week, November 14th, 2007

While both environmental and genetic factors contribute to the risk of developing alcohol dependence, it is believed to be a largely heritable – 52 to 64 percent – disease. Previous research had found a significant association between risk for alcoholism and DNA sequence variations called single nucleotide polymorphisms (SNPs) within the GABRA2 gene. New findings indicate that the GABRA2 genotype can modify overall drinking behavior, and may also have an impact on the success of certain types of alcohol psychotherapy.

Results are published in the November issue of Alcoholism: Clinical & Experimental Research.

"The Collaborative Study on the Genetics...

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