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Apoptosis Therapy

New apoptosis therapy research has been reported by scientists at Charite University

Published in Genetics and Environmental Health Week, March 12th, 2008

Investigators publish new data in the report 'Extreme variation in apoptosis capacity amongst lymphoid cells of Nijmegen breakage syndrome patients.' "The human genetic disorder, Nijmegen breakage syndrome (NBS), is characterised by radiosensitivity, immunodeficiency and an increased risk for cancer, particularly lymphoma. The NBS1 gene codes for a protein, nibrin, involved in the processing/repair of DNA double strand breaks and in cell cycle checkpoints," investigators in Germany report.

"The majority of patients (>90%) are homozygous for a founder mutation. Despite this genetic homogeneity, the syndrome shows considerable clinical variability, for example, in age...

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