Cleft Lip

New cleft lip study results from University of Bologna described

Published in Genetics and Environmental Health Week, June 25th, 2008

"Clefts of the orofacial region are among the most common facial defects and are caused by abnormal facial development during gestation. Cleft lip with or without cleft palate (CL/P) is a birth defect with a complex etiology resulting from a mixture of genetic and environmental factors," scientists writing in the European Journal of Oral Sciences report.

"In the present study we considered myosin 14 (MYH14) as a candidate gene for CL/P. This gene codes for the heavy chain of non-muscle myosin IIC (NMMHC-IIC), maps in the OFC3 region, and shares significant homology with myosin 9, a gene that our group has recently seen to be involved in CL/P. A linkage...

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Source: Genetics and Environmental Health Week (2008-06-25)

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