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Parkinson Disease

Research from D.G. Healy and co-authors provides new data about Parkinson disease

Published in Genetics and Environmental Health Week, August 20th, 2008

According to a study from London, the United Kingdom, " Mutations in LRRK2, the gene that encodes leucine-rich repeat kinase 2, are a cause of Parkinson's disease (PD). The International LRRK2 Consortium was established to answer three key clinical questions: can LRRK2-associated PD be distinguished from idiopathic PD; which mutations in LRRK2 are pathogenic; and what is the age-specific cumulative risk of PD for individuals who inherit or are at risk of inheriting a deleterious mutation in LRRK2' Methods Researchers from 21 centres across the world collaborated on this study."

"The frequency of the common LRRK2 Gly2019Ser mutation was estimated on the basis of data...

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