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Borrelia

Report summarizes borrelia study findings from City University of New York

Published in Genetics and Environmental Health Week, August 20th, 2008

"The A and B clones of Borrelia burgdorferi sensu stricto, distinguished by outer surface protein C (ospC) gene sequences, are commonly associated with disseminated Lyme disease, To resolve phylogenetic relationships among isolates, we sequenced 68 isolates from Europe and North America at 1 chromosomal locus (16S-23S ribosomal RNA spacer) and 3 plasmid loci (ospC, dbpA, and BBD14). The ospC-A clone appeared to be highly prevalent on both continents, and isolates of this clone were uniform in DNA sequences, which suggests a recent trans-oceanic migration," investigators in the United States report.

"The genetic homogeneity of ospC-A isolates was confirmed by sequences...

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