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Demyelinating Polyradiculoneuropathy Genetics

Research from King's College London, Department of Clinical Neuroscience yields new findings on demyelinating polyradiculoneuropathy genetics

Published in Genetics and Environmental Health Week, March 11th, 2009

Research findings, 'Humoral and cellular immune responses to myelin protein peptides in chronic inflammatory demyelinating polyradiculoneuropathy,' are discussed in a new report. "Evidence that chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an autoimmune disease was sought, by studying cellular and humoral immune responses to peripheral nerve myelin proteins. 40 CIDP, 36 healthy control subjects (HC) and subjects with non-immune mediated neuropathies (other neuropathies, ON) for antibodies were studied by ELISA and cellular responses by cytokine ELISPOT (INF gamma, IL10) and ELISA (IL17) to synthetic peptides representing P0, P2 and PMP22," researchers in London, the...

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