Genetics & Environmental Health Week
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Artificial Chromosomes
Research from Harvard University reveals new findings on artificial chromosomes
March 25th, 2009
"Pseudoautosomal regions (PARs) shared by avian Z and W sex chromosomes are typically small homologous regions within which recombination still occurs and are hypothesized to share the properties of autosomes. We capitalized on the unusual structure of the sex chromosomes of emus, Dromaius novaehollandiae, which consist almost entirely of PAR shared by both sex chromosomes, to test this hypothesis," investigators in the United States report. "We compared recombination, linkage disequilibrium (LD), GC content, and nucleotide diversity between pseudoautosomal and autosomal loci derived from 11 emu bacterial artificial chromosome (BAC) clones that were mapped to...
Source: Genetics & Environmental Health Week (2009-03-25)
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