Hypercholesterolemia
Research from K. Tveten and co-researchers provides new data on hypercholesterolemia
Published in Genetics and Environmental Health Week, June 3rd, 2009
"Familial hypercholesterolemia is caused by mutations in the low-density lipoprotein receptor (LDLR) gene. The synonymous mutation R385R has been shown to introduce a cryptic splice site in exon 9. The aims of this study were to establish to what extent the cryptic splice site is selected ahead of the normal splice site and to determine if the aberrant transcript is degraded by nonsense-mediated mRNA decay," investigators in Oslo, Norway report.
"The relative amount of the aberrant transcript was determined by real-time PCR and found to vary from 25% to 45% in heterozygous familial hypercholesterolemia individuals. Epstein-Barr virus-transformed lymphocytes were...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Genetics and Environmental Health Week
More Articles from Genetics and Environmental Health Week
- Allergies Risk Factors
Research reports on allergies risk factors from F. Sánchez-Valverde and colleagues provide new insights - Cancer Genetics
New cancer genetics research from Cancer Research Center outlined - Contact Dermatitis
Research findings from M.R.A. Hussein et al update understanding of contact dermatitis - Dementia
Findings in dementia reported from Medical University of Vienna - Genetics
New genetics study findings recently were reported by M.F. Leber and co-researchers - Hemochromatosis
Research conducted at W.H. Rogowski and co-authors has provided new information about hemochromatosis - More from this issue of Genetics and Environmental Health Week
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
