Life Sciences
New life sciences study results reported from University of Padova, Department of Biomedical Sciences
Published in Genetics and Environmental Health Week, June 3rd, 2009
Research findings, 'Comparative transcriptional and biochemical studies in muscle of myotonic dystrophies (DM1 and DM2),' are discussed in a new report. "Myotonic dystrophy type 1 (DM1) and myotonic dystrophy type 2 (proximal muscular myopaty/DM2) are caused by similar dynamic mutations at two distinct genetic loci. The two diseases also lead to similar phenotypes but different clinical severity," investigators in Padua, Italy report.
"Dysregulation of alternative splicing has been suggested as the common pathogenic mechanism. Here, we investigate the molecular differences between DM1 and DM2 using reverse transcriptase-polymerase chain reaction of troponin T (TnT) and...
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