Cancer Gene Therapy
Data on cancer gene therapy published by researchers at Indiana University, Department of Pediatrics
Published in Genetics and Environmental Health Week, January 6th, 2010
Data detailed in 'Retroviral vector integration in post-transplant hematopoiesis in mice conditioned with either submyeloablative or ablative irradiation' have been presented. According to recent research published in the journal Gene Therapy, "X-linked chronic granulomatous disease (X-CGD) is an inherited immunodeficiency with absent phagocyte NADPH-oxidase activity caused by defects in the gene-encoding gp91(phox). Here, we evaluated strategies for less intensive conditioning for gene therapy of genetic blood disorders without selective advantage for gene correction, such as might be used in a human X-CGD protocol."
"We compared submyeloablative with ablative...
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