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Choroidal Vasculopathy

Investigators at University of Yamanashi, Medical Department zero in on choroidal vasculopathy

Published in Genetics and Environmental Health Week, January 6th, 2010

In this recently published article, scientists in Yamanashi, Japan conducted a study "To investigate whether the LOC387715/ARMS2 variants are associated with an angiographic phenotype, including lesion size and composition, in subfoveal polypoidal choroidal vasculopathy. Ninety-two subjects with symptomatic subfoveal polypoidal choroidal vasculopathy, whose visual acuity was from 0.1 to 0.5 on the Landolt chart, were genotyped for the LOC387715 polymorphism (rs10490924) using denaturing high-performance chromatography."

"The angiographic phenotype, including lesion composition and size, was evaluated by evaluators who were masked for the genotype. Lesion size was...

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