Published in Genetics and Environmental Health Week, January 6th, 2010
"Here we analyzed the promoter methylation of 15 genes (RASSF1A, p16, MGMT, DAPK, RAR beta, MLH1, CDH1, GSTP1, RASSF2, RASSF4, RASSF5, MST1, MST2, LATS1, LATS2) in 54 HNSCC and in matching 23 normal tissues. Methylation of these tumor-related genes (TRG) was significantly more frequent in HNSCC (42%) compared to normal samples (23%; p<0.05). Particularly, methylation of p16 (60%), MGMT (53%), DAPK...
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