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Anemia

Research from Arabian Gulf University, Department of Medical Biochemistry provides new data about anemia

Published in Genetics and Environmental Health Week, March 3rd, 2010

Investigators publish new data in the report 'Human platelet alloantigens (HPA) 1, HPA2, HPA3, HPA4, and HPA5 polymorphisms in sickle cell anemia patients with vaso-occlusive crisis.' According to recent research from Manama, Bahrain, "Vaso-occlusive crisis (VOC) is a significant cause of morbidity and mortality in sickle cell anemia (SCA) patients. Insofar as polymorphism in human platelet alloantigen (HPA) exhibit a prothrombotic nature, we hypothesized that specific HPA polymorphic variants are associated with VOC."

"We investigated the distribution of HPA1, HPA2, HPA3, HPA4, and HPA5 alleles genotypes among VOC and non-VOC control SCA patients. This was a...

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