Genetics

Researchers from University of North Carolina describe findings in genetics

Published in Genetics and Environmental Health Week, March 10th, 2010

"To identify genetic variants with modest effects on complex human diseases, a growing number of networks or consortia are created for sharing data from multiple genome-wide association studies on the same disease or related disorders. A central question in this enterprise is whether to obtain summary results or individual participant data from relevant studies," scientists in the United States report.

"We show theoretically and numerically that meta-analysis of summary results is statistically as efficient as joint analysis of individual participant data (provided that both analyses are performed properly under the same modeling assumptions). We illustrate this...

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Source: Genetics and Environmental Health Week (2010-03-10)

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