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Infectious Diseases Therapy

Investigators at University of Pittsburgh, Division of Infectious Diseases release new data on infectious diseases therapy

Published in Genetics and Environmental Health Week, March 10th, 2010

Scientists discuss in 'Low frequency nonnucleoside reverse-transcriptase inhibitor-resistant variants contribute to failure of efavirenz-containing regimens in treatment- experienced patients' new findings in infectious diseases. According to recent research published in the Journal of Infectious Diseases, "The contribution of low frequency drug-resistant human immunodeficiency virus type 1 (HIV-1) variants to failure of antiretroviral therapy is not well defined in treatment-experienced patients. We sought to detect minor nonnucleoside reverse-transcriptase inhibitor (NNRTI)-resistant variants at the initiation of multidrug efavirenz-containing therapy in both NNRTI-naive and...

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