Academia Sinica, Taipei
Novel assay provides quantitative measure of synaptic GABA antagonist effects
Published in Genetics and Environmental Law Weekly, October 8th, 2005
"Paired-pulse facilitation (PPF) is a form of short-term plasticity that can be used qualitatively to characterize the synaptic effects of neuroactive compounds," researchers in Taiwan explained.
"As we have shown previously, CNQX has a marked effect on PPF which can be measured quantitatively," noted S.O. Sylantyev and colleagues at Academia Sinica in Taipei. In their subsequent study, the collaborators sought to identify "quantitatively possible differences in the effects of the post- and presynaptic GABA antagonists on PPF in vitro."
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