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CHU Pitie Salpetriere, Paris

Adeno-associated virus type-2 infection reduces the grafted cell survival

Published in Genetics and Environmental Law Weekly, January 14th, 2006

A study from France has reported on the efficiency of adeno-associated virus type-2 vectors in non-human primate Schwann cells.

"Adult macaque Schwann cells were infected using adeno-associated virus type-2-derived vectors expressing the green fluorescent protein reporter gene under the control of the cytomegalovirus, the hybrid cytomegalovirus-beta actin, the myelin basic protein or the tetracycline-inducible promoters," wrote C. Girard and colleagues, CHU Pitie Salpetriere.

"On the basis of green fluorescent protein expression, gene transfer efficiency was compared in resting and dividing conditions following or not following hydroxyurea or...

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