Novartis

AMN107 can produce dramatic benefits in some forms of leukemia resistant to Gleevec

Published in Genetics and Environmental Law Weekly, January 14th, 2006

The targeted agent AMN107 can produce dramatic benefits in patients with some forms of leukemia that are resistant to Gleevec, the standard therapy for these cancers, according to researchers at The University of Texas M.D. Anderson Cancer Center.

At the 47th Annual Meeting of the American Society of Hematology (ASH), the investigators reported marked improvement in outcome in all three phases of chronic myeloid leukemia (CML) as well as benefit in treating a form of acute lymphocytic leukemia (ALL) that shares the same genetic abnormality as CML, the Philadelphia chromosome.

"This drug is very promising and appears at this point to offer an...

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Source: Genetics and Environmental Law Weekly (2006-01-14)

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