Published in Genetics and Environmental Law Weekly, January 14th, 2006
According to recent research from the United States, "The band 4.1 proteins are cytoskeletal proteins, harboring a conserved FERM domain highly homologous to the N-terminal FERM domain of ezrin, radixin, moesin, and merlin. Recently, a truncated form of the 4.1B protein, termed Dal-1, was identified in a screen as down regulated in adenocarcinoma of the lung and was mapped to chromosome 18p11.3, which is lost in 38% of primary non-small cell lung carcinoma tumors."
"Analysis of several meningiomas has shown that Dal-1 expression was lost in 76% of the tumors. To...
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