Postgraduate Institute of Medical Education & Research, India
Mycobacterium tuberculosis antigen was expressed to study its immunoprophylactic potential
Published in Genetics and Environmental Law Weekly, October 14th, 2006
"Secreted proteins encoded by different regions of difference (RDs) from the genome of Mycobacterium tuberculosis have been considered as attractive candidates for vaccination against tuberculosis owing to their absence in most BCG strains. In this study, the structural gene for the RD2 locus encoding protein CFP21 was PCR amplified and expressed as a fusion protein with hexahistidine residues in Escherichia coli," researchers in India report.
"Expression of CFP21 in E. coli...
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