Genome Institute of Singapore, Singapore
Aberrant gene expression profile is observed in cloned mouse embryos
Published in Genetics and Environmental Law Weekly, October 14th, 2006
"Somatic cell nuclear transfer has successfully been used to clone several mammalian species including the mouse, albeit with extremely low efficiency. This study investigated gene expression in cloned mouse embryos derived from cumulus cell donor nuclei, in comparison with in vivo fertilized mouse embryos, at progressive developmental stages," wrote G.Q. Tong and colleagues, Genome Institute of Singapore.
"Enucleation was carried out by the conventional puncture method rather than by the...
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