Stanford University, U.S.
Studies from Germany and Switzerland advance knowledge in cardiology research
Published in Genetics and Environmental Law Weekly, October 14th, 2006
Study 1: Adenoviral human BCL-2 transgene expression attenuates early donor cell death after cardiomyoblast transplantation into ischemic rat hearts.
"Cell transplantation for myocardial repair is limited by early cell death. Gene therapy with human Bcl-2 (hBcl-2) has been shown to attenuate apoptosis in the experimental setting. Therefore, we studied the potential benefit of hBcl-2 transgene expression on the survival of cardiomyoblast grafts in ischemic rat hearts," scientists writing in the journal Circulation report.
"H9c2 rat cardiomyoblasts...
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