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Hepatitis B Virus Epidemiology

Recent findings from Second Military Medical University, Department of Epidemiology highlight research in hepatitis B virus epidemiology

Published in Genetics and Environmental Law Weekly, April 21st, 2007

A report, "Improved multiplex-PCR to identify hepatitis B virus genotypes A-F and subgenotypes B1, B2, C1 and C2," is newly published data in Journal of Clinical Virology. "There are eight genotypes (A-H) and numerous subgenotypes of hepatitis B virus (HBV). The genotype has been shown to affect the course of HBV infection. To develop an efficient genotyping and subgenotyping method for large-scale epidemiological surveys of HBV infection in countries with high prevalence of HBV B and C such as China. We designed genotype and subgenotype-specific primer pairs, and adjusted PCR conditions for a multiplex-PCR using common Taq polymerase to identify HBV genotypes A-F in one reaction...

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