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Acute Myeloid Leukemia

Data on acute myeloid leukemia detailed by researchers at National University

Published in Genetics and Environmental Law Weekly, August 4th, 2007

According to recent research published in the journal Cancer Genetics and Cytogenetics, "Cytogenetics represents the most valuable predictor for a poor outcome in patients with acute myeloid leukemia (AML), but it encompasses a heterogeneous patient population who might have diverse pathogenesis and clinical courses. In particular, the significance of complex chromosome aberrations within this cohort has seldom been addressed before."

"We analyzed 48 AML patients with adverse-risk cytogenetics in this study. The complex karyotype (three or more numerical/structural cytogenetic changes; 29 patients) was found to occur more frequently among the elderly than a...

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