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Cancer Therapy

New cancer therapy study findings have been reported by scientists at University of Texas

Published in Genetics and Environmental Law Weekly, August 18th, 2007

A report, "Structural basis for the inhibition of the LSD1 histone demethylase by the antidepressant trans-2-phenylcyclopropylamine," is newly published data in Biochemistry. According to a study from the United States, "Histone modifications, such as acetylation and methylation, are important epigenetic marks that regulate diverse biological processes that use chromatin as the template, including transcription. Dysregulation of histone acetylation and methylation leads to the silencing of tumor suppressor genes and contributes to cancer progression."

"Inhibitors of enzymes that catalyze the addition and removal of these epigenetic marks thus have therapeutic...

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