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Alzheimer Disease Genetics

Research from Chinese Academy of Medical Sciences has provided new data on Alzheimer disease genetics

Published in Genetics and Environmental Law Weekly, May 17th, 2008

A report, 'Association of NAD(P)H:quinone oxidoreductase 1 polymorphism and Alzheimer's disease in Chinese,' is newly published data in Journal of Molecular Neuroscience. According to a study from Beijing, People's Republic of China, "Several lines of evidence support a role of oxidative stress in the pathology of Alzheimer's disease (AD). NAD(P)H:quinone oxidoreductase 1 (NQO1) catalyzes the two-electron reduction of quinones, preventing their participation in redox cycling and subsequent generation of reactive oxygen species."

"We examined association between the NQO1 C609T gene polymorphism and sporadic AD in a Chinese population comprising 311 AD patients and...

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