Cell Transplantation

Research conducted at University College has updated our knowledge about cell transplantation

Published in Genetics and Environmental Law Weekly, December 6th, 2008

"Haematopoietic stem cell transplantation (HSCT), using unrelated donors (UD), is now a common modality of treatment for individuals with a variety of different diseases. HLA matching has been shown to have a significant impact on patient outcome," scientists in London, the United Kingdom report.

"This study includes 423 unrelated UK patient/donor pairs. The patients and donors were typed at high resolution for HLA-A, -B, -C, -DRB1, -DQB1, -DPB1. The degree and type of HLA mismatch was found to be a significant factor affecting outcome. The matching status for DPB1, both at an allele and epitope level, significantly affected transplant complications," wrote B.E. Shaw...

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Source: Genetics and Environmental Law Weekly (2008-12-06)

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