Published in Genetics and Environmental Law Weekly, February 14th, 2009
"A novel peptide ligand, A5-1 (VILVLF), with high affinity to integrin alpha 5 beta 1 was identified from the hexapeptide libraries with this chip-based screening method on the basis of a competitive inhibition assay. A5-1 inhibits the integrin-fibronectin interaction in a dose-dependent manner (IC50; 1.56 +/- 0.28 mc M. In addition, it...
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