Acute Myeloid Leukemia

Research in the area of acute myeloid leukemia reported from T.A. Fehniger and colleagues

Published in Genetics and Environmental Law Weekly, March 21st, 2009

According to a study from the United States, "Patients with acute myeloid leukemia (AML) frequently fail chemotherapy due to refractory disease, relapse, or toxicity. Among older AML patients (age > 60 years), there are few long-term survivors."

"Lenalidomide is a candidate for study in AML based on its clinical activity in a related disorder, myelodysplastic syndrome (MDS), with the 5q- chromosomal abnormality. We report induction of sustained morphologic and cytogenetic complete remission in 2 older AML patients treated with high-dose, single-agent lenalidomide; each patient had trisomy 13 as the sole cytogenetic abnormality. We show for the first time that...

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Source: Genetics and Environmental Law Weekly (2009-03-21)

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