Peripheral Neuropathy Genetics
New peripheral neuropathy genetics research from Kyoto University outlined
Published in Genetics and Environmental Law Weekly, May 16th, 2009
Investigators publish new data in the report 'Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice.' "The non-obese diabetic (NOD) mouse strain is prone to developing various autoimmune syndromes including type I diabetes mellitus (T1DM), sialadenitis, thyroiditis and pancreatitis. Although the genetic basis of T1DM has been extensively analyzed, genetic factors that modify the other autoimmune phenotypes are largely unknown," scientists in Kyoto, Japan report.
"We have recently reported that NOD mice with anti-diabetogenic MHC haplotype (H-2(b)) and programmed cell death 1 (PD-1) deficiency (NOD.H2(b)-Pdcd1(-/-) mice) are protected from...
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