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Pituitary Cancer Genetics

Researchers from National Institute of Diabetes and Digestive and Kidney Disease describe findings in pituitary cancer genetics

Published in Genetics and Environmental Law Weekly, May 23rd, 2009

Research findings, 'The MEN1 gene and pituitary tumours,' are discussed in a new report. According to a study from the United States, "Sporadic multiple endocrine neoplasia type 1 (MEN1) is defined as the occurrence of tumours in two of three main endocrine tissue types: parathyroid, pituitary and pancreaticoduodenal. A prolactinoma variant or Burin variant of MEN1 was found to occur in three large kindreds, with more prolactinomas and fewer gastrinomas than typical MEN1."

"MEN1 tumours differ from common tumours by showing features from the MEN1 gene (e.g. larger pituitary tumours). They also show various expressions of tumor multiplicity; however, pituitary tumor in...

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