Alzheimer Disease

Research from University of Kansas, Medical Department provides new data on Alzheimer disease

Published in Genetics and Environmental Law Weekly, November 7th, 2009

According to recent research from the United States, "Exercise and cardiorespiratory (CR) fitness may moderate age-related regional brain changes in nondemented (ND) older adults. The relationship of fitness to Alzheimer disease (AD)-related brain change is understudied, particularly in the hippocampus, which is disproportionately affected in early AD."

"The role of apolipoprotein E4 (apoE4) genotype in modulating this relationship is also unknown. ND (n = 56) and early-stage AD patients (n = 61) over the age of 65 years had magnetic resonance imaging and CR fitness assessments. Voxel-based morphometry techniques were used to identify AD-related atrophy. We analyzed the...

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Source: Genetics and Environmental Law Weekly (2009-11-07)

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