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BioMed Central

Lung tissue generated from human embryonic stem cells

Published in Genetics and Environmental Law Weekly, November 21st, 2009

Scientists in Belgium have successfully differentiated human embryonic stem cells (hESC) into major cell types of lung epithelial tissue using a convenient air-liquid interface. The technique, published in BioMed Central's open access journal Respiratory Research, could provide an alternative to lung transplants for patients with lung injury due to chronic pulmonary disease and inherited genetic diseases such as cystic fibrosis.

Lindsey Van Haute and colleagues from the Department of Embryology and Genetics at the Free University of Brussels (Vrije Universiteit Brussel) demonstrated for the first time that hESC could be converted into epithelial-like cells in human...

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