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Multiplex PCR

Studies by R. Pereira and co-authors describe new findings in multiplex PCR

Published in Genetics and Environmental Law Weekly, January 30th, 2010

"Human identification is usually based on the study of STRs or SNPs depending on the particular characteristics of the investigation. However, other types of genetic variation such as insertion/deletion polymorphisms (indels) have considerable potential in the field of identification, since they can combine the desirable characteristics of both STRs and SNPs," scientists in Oporto, Portugal report.

"In this study, a set of 38 non-coding bi-allelic autosomal indels reported to be polymorphic in African, European, and Asian populations were selected. We developed a sensitive genotyping assay, which is able to characterize all 38 bi-allelic markers using a single multiplex...

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