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Parkinson's Disease

Reports from L. Samaranch and co-researchers add new data to research in Parkinson's disease

Published in Genetics and Environmental Law Weekly, March 6th, 2010

According to recent research published in the European Journal of Neurology, "Linkage analysis in familial Parkinson's disease (PD) identified a locus in 2q36-37 (PARK11). Sequencing of GIGYF2 identified several variants only present amongst PD individuals."

"We analyzed the presence of disease-associated GIGYF2 variants in familial and sporadic PD from Spanish origin by sequencing of 147 PD individuals. The entire GIGYF2 coding sequence was analyzed in 122 familial PD individuals and exons 2, 4, 8-11, 14 and 25-26 were sequenced in 25 sporadic PD to identify disease-associated variants. We found no variants associated with PD and failed to identify any of...

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