Enzyme Research
Researchers from University of Iowa, Department of Pharmacology publish new studies and findings in the area of enzyme research
Published in Genetics and Environmental Law Weekly, April 3rd, 2010
Current study results from the report, 'Transactivation of the epidermal growth factor receptor is involved in the lutropin receptor-mediated down-regulation of ovarian aromatase expression in vivo,' have been published. According to a study from the United States, "Ovarian follicular development and differentiation is characterized by dramatic changes in aromatase (Cyp19a1) expression. In preovulatory follicles, activation of the FSH receptor increases aromatase expression until the surge of LH decreases it."
"Here we provide in vivo evidence that down-regulation of Cyp19a1 by the LH surge requires efficient signaling through the epidermal growth factor receptor...
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