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Addiction Medicine

Data on addiction medicine discussed by researchers at University of Colorado

Published in Genetics and Environmental Law Weekly, April 3rd, 2010

"The reasons why people smoke are varied, but research has shown that genetic influences on various aspects of nicotine addiction are a major factor. There also is a strong genetic influence on measures of nicotine sensitivity in mice," scientists writing in the journal Pharmacogenetics and Genomics report.

"Despite the established contribution of genetics to nicotine sensitivity in mice and humans, no naturally occurring genetic variation has been identified that demonstrably alters sensitivity to nicotine in either species. However, one genetic variant has been implicated in altering nicotine sensitivity in mice is a T529A polymorphism in Chrna4, the gene that...

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