Published in Genomics and Genetics Weekly, November 8th, 2002
siRNA are double-stranded RNA of approximately 20 base pairs that block or decrease the expression of specific gene targets. A comprehensive study of siRNA is proposed in this grant with aims of improving the basic technology by improving target site selection, optimizing delivery of the siRNA into cells, and characterizing the general features of siRNA that maximize its efficacy.
siRNA technology will enable researchers to...
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