Genomics and Genetics Weekly
Susan Hasty, Publisher
Table of Contents . . . May 9th, 2003
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Genomics and Genetics Weekly | Other Publications
Human Genome - Browser provides a portal for scientific exploration of finished sequence
Huntington Disease - Emory University researchers study earliest signs of disease
Cardiac Contractility - AT1 R gene expression has role for T3-induced vascular relaxation
Gene Transcription - IL-3 stimulation activates PU.1 transcription factor through p38(MAPK) pathway
Oncogenesis - Hepatitis infections may disable repair genes by promoter hypermethylation
Renal Disease - Laser microdissection facilitates analysis of angiogenic genes in the kidneys
Acute Myeloid Leukemia - Genetic risk factors identified in mice
Alzheimer Disease - Three new products launched for detecting genetic mutations
Arrhythmia - Heart disease among some Japanese may be due to gene sequencing variation
Atherosclerosis - Gene variation in immune system cells lowers heart disease risk
Autosomal Recessive Disorders - Carrier frequency of V377l (1129G > A) MVK mutation studied in the Netherlands
B Cell Regulation - Pten in B cells controls homeostasis and IgG class switch recombination
Breast Cancer - Rare metaplastic breast malignancies often reveal extensive vascularity
Breast Cancer - TP53 mutations may occur in familial breast cancer
Breast Cancer - Two biomarkers are valuable for predicting women's response to tamoxifen
Cancer Therapy - Company provides update on pipeline of marine compounds
Cancer Therapy - Lung cancer study combines gene expression and protein expression
Cancer Therapy - New findings published on diagnostic applications of HAAH Oncology Program
Cardiomyopathies - Models combining genetic effects useful in study
Cloning - Human clones may be impossible with current techniques, monkey study suggests
Combined Immunodeficiency - Defective DNA repair, increased genomic instability is the cause
Cytokine Induced Abortion - IL-1 receptor antagonist IL1RN*3 allele predisposes for spontaneous abortion
DNA Methylation - Regulation of gene expression is a dynamic response to environmental signals
DNA Transcription - AP-2 alpha's DNA binding is enhanced by the oncogene DEK
Down Syndrome - Study suggests link to neural tube defects
Environmental Toxins - Environmental Health Institute announces advances in genomics
Enzymology - Serine proteases appear to modulate vascular function and angiogenesis
Fitness - Physical activity in the elderly ruled in part by genetics
Gene Expression - Northeastern University enters genomics discovery agreement
Gene Mapping - Complete activity of genes documented for both healthy and cancerous cells
Genome Research - International consortium completes Human Genome Project
Genomics - The genomes of four advanced model organisms have been sequenced
HIV/AIDS Genomics and Genetics - Standard viral genotyping systems suitable for use with non-subtype B strains
HIV/AIDS Pathogenesis - CX3CR1 mutation linked to rapid disease progression
HLA-B Alleles - HLA-B*5130 is a new allele carrying a rare nucleotide substitution in exon 4
Heart Transplantation - Haplotypes rather than genotypes affect CsA disposition in transplant patients
Hepatitis C Virus - New research establishes genetic associations
Information Technology - The UMD-p53 database is useful for research on p53 related mutations
Juvenile Idiopathic Arthritis - Another susceptibility gene was found in the HLA class I region
Juvenile Polyposis - A BMPR1A germline mutation occurs in juvenile polyposis without SMAD4 mutation
Leukemia - The c-Myc oncoprotein interacts with Bcr
MHC Class I - A cluster of TRIM genes share a conserved coiled coil region
Multiple Sclerosis - Mutations in toll-like receptor 4 are at the same frequency as in normals
Occupational Exposure - TP53 mutations may act as fingerprints for exposure to specific carcinogens
Oncology - Differential tumor markers can track breast cancer characteristics
Personnel - Edwards named to lead the structural genomics consortium
Pregnancy Loss - Genotypes are evidence that these cytokines are important in pathogenesis of RPL
Progeria Syndrome - Genetic basis for premature aging found
Protein Arrays - A cell-free, direct protein synthesis method from DNA has been developed
Q Fever - Genetic blueprint for bacterium unveiled
Radiation Damage - No chromosomal instability was found in radiation exposed normal fibroblasts
Rapid Detection Assays - Lawrence Livermore National Laboratory signed to eTag service, supply deal
Severe Acute Respiratory Syndrome - CDC lab sequences genome of new coronavirus
Skin Cancers - Approximately half of all skin cancers have TP53 mutations
TB Pathogenesis - Scientists find genetic key to TB bacteria survival in lung cells
Th2 Responses - Protein kinase A regulates activation of IL-5 gene expression
Thyroid Cancer - Common thyroid cancer gene mutation found
Tuberculosis - Lost genes lend new strength to TB vaccine
Viral Genomics - The nuclear orphan receptor TR4 suppresses hepatitis B virus core promoter
Virology - Core-envelope 1-based assays can quickly distinguish hepatitis C virus subtypes
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