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Genomics and Genetics Weekly

Susan Hasty, Publisher

Table of Contents . . . May 16th, 2003

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Genomics and Genetics Weekly | Other Publications

Gene Regulation - Novel method identifies 'hidden' genes

Melanoma - Responsible gene discovered

Amyotrophic Lateral Sclerosis - Genetic abnormalities found in some ALS patients

Cell Biology - Structure reveals key to important gene regulator

Human Genome - There may be twice as many genes as previously thought

Obesity Therapy - Researchers find obesity receptor

AIDS Therapies - Phenotypic drug susceptibility data correlate with improved long-term outcomes

Amyotrophic Lateral Sclerosis - Mitochondrial DNA does not have mutations affecting normal respiratory function

Bacteriology - Sloppy repair helps tuberculosis bug resist drugs

Bioengineering - Macromolecular carriers play an integral role in modulating cancer activity

Bioethics - A Catholic theological vision for genomics is addressed

Bipolar Disorder - Gene variation raises risk

Breast Cancer - Gene expressed in 80% of patients

Breast Cancer - Race cited in gene study

Cancer Genomics - Tumors secrete factors and receptors that encourage endothelial cell mechanisms

Cancer Risk Factors - New study set to help women at high risk of breast or ovarian cancer

Cardiac Hypertrophy/Fibrosis - Grb2-p38 MAPK signaling pathway has an essential role

Cell Biology - Research reveals the magic behind merlin

Chlamydia - Small genome variations account for wide range of diseases, victims

Cloning - Cloned pigs differ from originals in looks and behavior

Collaborations - Chemogenomic profiling relationship initiated

Costello Syndrome - Report of child requiring anesthesia for laryngoscopy, bronchoscopy presented

Diabetes Genomics and Genetics - C-reactive protein promoter polymorphism associated with type 2 diabetes

Diabetes Genomics and Genetics - Novel mutation in lamins A and C linked to new clinical condition

Diabetes Genomics and Genetics - PAX4 mutation (R121W) is a prodiabetic variant in Okinawans

Diabetes Genomics and Genetics - Resistin gene polymorphism associated with type 2 diabetes and hypertension

Drug Development - Family of G-protein coupled receptor genes defined

Fabry Disease - FDA approves first treatment

Fabry Disease - Novel 6 bp insertion in exon 7 associated with unusual phenotype in family

Facilities - Duke opens genomics research center

Gene Discovery - Unique method developed for function-based identification of genes

Gene Sequencing - Technique produces comprehensive view of transcriptomes

Genetic Testing - Company enlists clinical laboratories for early access program

Genomics - Genes required for mycobacterial growth defined by high density mutagenesis

Genomics - Potential role identified for Wnt signaling in hematopoietic recovery

Genomics - Researchers identify genes responsible for osteoblast differentiation

Genomics - Scientists identify functionality of parasital enzyme insertions

Genomics and Genetics - Preliminary linkage map of the tick, Ixodes scapularis, released

Hematology - Conditioning irradiation induces radio-adaptive responses in stem cells

Hepatitis C Therapy - Combination therapy yields a better response in patients with HCV genotype 6

Hepatitis C Virus - The genotypes of HCV NS3 ATPases/helicases exhibit a variety of properties

Immunology - Angiogenic transcripts prevail in the nasal fluids of allergy sufferers

Immunology - CD25 depletion delayed growth of parasitaemia during parasite challenge

Immunology - Researchers describe method for identifying distribution of CD30 alleles

Leukemia - Imatinib mesylate abates growth factor secretion in chronic myelogenous leukemia

Leukemia - Researchers use DNA chips to determine how cells respond to different drugs

Liver Cancer - High rates of mitochondrial DNA mutations preface hepatocellular carcinoma

Liver Disease - Transglutaminase type II protects liver tissues from injury

Obesity Pathogenesis - Hyperphagia, not hypometabolism, causes early onset obesity

Oncogenes - Survey of cancer genes uncovers Viking roots

Oral Cancer - Genomic dissection used to characterize cancerous oral epithelium tissues

Otology - Ink4d a good candidate gene for inherited progressive hearing loss

Ovarian Cancer - Study suggests cells can alter surroundings to promote chemotherapy resistance

Research Funding - Gates Foundation gives $70 million for genome research

Stem Cell Research - Mouse model indicates BMSC associated with vascular cells

Therapy - Data suggests humoral immune responses play role in amodiaquine treatment

Tissue Typing - A rare HLA-B allele B*4408 is identified and there is a test for it

Tuberculosis - Interleukin-12 receptor beta1 polymorphisms influence susceptibility

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